Better hormonal methods

Natalie was deeply frustrated by her lack of feminization after 3 years of hormone therapy.  She certainly experienced the side-effects but didn't get the feminization she urgently craved.

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After gender reassignment surgery

Wendy had gender reassignment surgery in her mid-20s.  Once post-op she was maintained on 2mg of micronized oral estradiol a day for many years.  Little did she know that 2 mg estradiol wasn't actually what she was getting.